- Chemical Name: Mal-PEG2-alcohol
- CAS No.: 34321-81-8
Quality products?make an important contribution to long-term revenue and profitability. Mal-PEG2-alcohol Good Supplier In Bulk Supply High Purity 34321-81-8
1.What is the Mal-PEG2-alcohol ?
Used in Pharmaceutical Industry:
Mal-PEG2-alcohol is used as a molecular linker for improving the solubility and stability of therapeutic biomolecules. Its ability to form covalent bonds with thiol groups allows for the attachment of drugs or other bioactive molecules to the PEG chain, potentially enhancing their pharmacokinetic properties and reducing immunogenicity.
Used in Drug Delivery Systems:
In the field of drug delivery, Mal-PEG2-alcohol serves as a key component in the design of targeted drug carriers. The maleimide group can be utilized to attach drug molecules or targeting ligands to the PEGylated carrier, enabling selective delivery to specific cells or tissues. This targeted approach can improve the efficacy of the drug and reduce side effects.
Used in Bioconjugation:
Mal-PEG2-alcohol is used as a bioconjugation agent to covalently link biomolecules, such as proteins or peptides, with a thiol group to other molecules or surfaces. This can be particularly useful in the development of biosensors, immobilized enzymes, or antibody-drug conjugates.
Used in Cosmetics Industry:
In the cosmetics industry, Mal-PEG2-alcohol is used as a solubility enhancer for hydrophobic active ingredients. The hydrophilic PEG spacer can improve the dispersion and stability of these ingredients in cosmetic formulations, ensuring their effectiveness and ease of application.
Used in Diagnostics:
Mal-PEG2-alcohol can be employed in the development of diagnostic tools, such as imaging agents or affinity reagents. The ability to form covalent bonds with thiol-containing biomolecules allows for the creation of stable conjugates that can be used for detecting specific targets in biological samples.
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55750-48-6
N-methoxycarbonylmaleimide
-
-
929-06-6
2-(2-Aminoethoxy)ethanol
-
-
34321-81-8
1-(2-(2-hydroxyethoxy)ethyl)-1H-pyrrole-2,5-dione
| Conditions | Yield |
|---|---|
|
With
sodium hydrogencarbonate;
at 0 - 23 ℃;
for 1h;
|
93%
|
|
With
sodium hydrogencarbonate;
In
water;
at 0 - 20 ℃;
for 0.833333h;
|
90%
|
|
With
sodium hydrogencarbonate;
In
water;
at 0 - 20 ℃;
for 1.16667h;
|
73%
|
|
With
sodium hydrogencarbonate;
|
61%
|
|
With
sodium hydrogencarbonate;
In
water;
at 0 - 20 ℃;
|
57%
|
|
With
sodium hydrogencarbonate;
In
water;
at 0 - 20 ℃;
for 3.5h;
|
53%
|
|
With
sodium hydrogencarbonate;
In
water;
at 0 - 20 ℃;
for 0.833333h;
Inert atmosphere;
|
44%
|
|
With
sodium hydrogencarbonate;
at 0 - 20 ℃;
|
4.37 g
|
-
![N-[2-(2-hydroxyethoxy)ethyl]-exo-3,6-epoxy-1,2,3,6-tetrahydrophthalimide](/upload/2026/6/98f159aa579f484fab5ad334beb391de_5a734a25-b171-48d2-a042-511d71eba6c1.png)
-
916852-34-1
N-[2-(2-hydroxyethoxy)ethyl]-exo-3,6-epoxy-1,2,3,6-tetrahydrophthalimide
-
-
34321-81-8
1-(2-(2-hydroxyethoxy)ethyl)-1H-pyrrole-2,5-dione
| Conditions | Yield |
|---|---|
|
In
toluene;
for 7h;
Reflux;
|
41%
|
2.What is the CAS number for Mal-PEG2-alcohol ?
The CAS number of Mal-PEG2-alcohol is 34321-81-8.
More information of Mal-PEG2-alcohol 34321-81-8 are:
|
CAS?Number |
34321-81-8 |
|
Density |
1.317±0.06 g/cm3(Predicted) |
|
Boiling Point |
361.7±22.0 °C(Predicted) |
|
PSA |
66.84000 |
|
LogP |
-1.14180 |
|
Pka |
14.35±0.10(Predicted) |
3.What are another words for Mal-PEG2-alcohol ?
Synonyms?for?Mal-PEG2-alcohol 34321-81-8:
4.What is the molecular formula of Mal-PEG2-alcohol?
The chemical formula of ?Mal-PEG2-alcohol is?C8H11NO4 which containing 8 Carbon atoms,11 Hydrogen atoms,1 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of??Mal-PEG2-alcohol?is 185.18.
5.What is Mal-PEG2-alcohol (34321-81-8) used for?
Mal-PEG2-alcohol is a PEG linker containing a maleimide group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Relevant articles related to Mal-PEG2-alcohol:
|
Article |
Source |
|
Synthesis, characterization, and in vivo delivery of siRNA-squalene nanoparticles targeting fusion oncogene in papillary thyroid carcinoma |
Raouane, Mouna,Desmaele, Didier,Gilbert-Sirieix, Marie,Gueutin, Claire,Zouhiri, Fatima,Bourgaux, Claudie,Lepeltier, Elise,Gref, Ruxandra,Ben Salah, Ridha,Clayman, Gary,Massaad-Massade, Liliane,Couvreur, Patrick , p. 4067 - 4076 (2011) |
|
Linker, linker-containing antibody conjugate drug and application of linker |
- Paragraph 0171-0173; 0183; 0187-0188, (2020/02/20) |
6.Buy Mal-PEG2-alcohol with the best price .
Shanghai Qinsheng Pharmaceutical Technology Co.,Ltd. is a quality supplier of Mal-PEG2-alcohol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Mal-PEG2-alcohol 34321-81-8.