Home >Pharmaceutical > (S)-3-(4-HYDROXYPHENYL)-2-HYDROXYPROPIONIC ACID
- Chemical Name: (S)-3-(4-HYDROXYPHENYL)-2-HYDROXYPROPIONIC ACID
- CAS No.: 23508-35-2
(S)-3-(4-HYDROXYPHENYL)-2-HYDROXYPROPIONIC ACID GMP Manufacturer Global Trade 23508-35-2 with Fast Delivery
- Molecular Formula: C9H10O4
- Molecular Weight: 182.176
- Vapor Pressure: 0mmHg at 25°C
- Melting Point: 165-168 °C
- Refractive Index: 1.617
- Boiling Point: 414.439 °C at 760 mmHg
- PKA: 3.80±0.10(Predicted)
- Flash Point: 218.597 °C
- PSA： 77.76000
- Density: 1.405 g/cm3
- LogP: 0.38020
(S)-3-(4-HYDROXYPHENYL)-2-HYDROXYPROPIONIC ACID(Cas 23508-35-2) Usage
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General Description |
(S)-3-(4-HYDROXYPHENYL)-2-HYDROXYPROPIONIC ACID, also known as caffeic acid, is a natural organic compound found in various plants. It is a hydroxycinnamic acid that belongs to the phenolic group of compounds and is a potent antioxidant. Caffeic acid has been shown to have anti-inflammatory and neuroprotective effects, and may also have potential anti-cancer properties. It is commonly found in foods such as coffee, fruits, vegetables, and wine, and is considered to be a beneficial dietary component due to its antioxidant and potential health-promoting properties. |
InChI:InChI=1/C9H10O4/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8,10-11H,5H2,(H,12,13)/t8-/m0/s1
23508-35-2 Relevant articles
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Kotake
, p. 414 (1910)
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Sasaki,Otsuka
, p. 535 (1917)
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Aeruginosins 102-A and B, new thrombin inhibitors from the cyanobacterium Microcystis viridis (NIES-102)
Matsuda, Hisashi,Okino, Tatsufumi,Murakami, Masahiro,Yamaguchi, Katsumi
, p. 14501 - 14506 (1996)
Aeruginosins 102-A and B were isolated f...
A Phenylpyruvic Acid Reductase Is Required for Biosynthesis of Tropane Alkaloids
Qiu, Fei,Yang, Chunxian,Yuan, Lina,Xiang, Dan,Lan, Xiaozhong,Chen, Min,Liao, Zhihua
, p. 7807 - 7810 (2018)
Solanaceous medicinal plants produce tro...
Synthesis of Weinreb amides using diboronic acid anhydride-catalyzed dehydrative amidation of carboxylic acids
Shimada, Naoyuki,Takahashi, Naoya,Ohse, Naoki,Koshizuka, Masayoshi,Makino, Kazuishi
supporting information, p. 13145 - 13148 (2020/11/09)
The first successful example of the dire...
Mechanistic study of the radical SAM-dependent amine dehydrogenation reactions
Ji, Xinjian,Liu, Wan-Qiu,Yuan, Shuguang,Yin, Yue,Ding, Wei,Zhang, Qi
, p. 10555 - 10558 (2016/09/02)
The radical SAM enzyme NosL catalyzes th...
Latifolicinin A from a Fermented Soymilk Product and the Structure-Activity Relationship of Synthetic Analogues as Inhibitors of Breast Cancer Cell Growth
Ke, Yi-Yu,Tsai, Chen-Hsuan,Yu, Hui-Ming,Jao, Yu-Chen,Fang, Jim-Min,Wong, Chi-Huey
, p. 9715 - 9721 (2015/11/24)
The functional components in soymilk may...
23508-35-2 Process route
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156-39-8
4-hydroxyphenylpiruvic acid
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-
6482-98-0,23508-35-2,89919-57-3,306-23-0
2-hydroxy-3-(4-hydroxyphenyl)propanoic acid
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556-02-5,556-03-6,34537-57-0,55520-40-6,96946-98-4,60-18-4,18875-48-4,25619-78-7,30704-25-7
?Tyr
| Conditions | Yield |
|---|---|
|
With
[Ir(III)Cp*(bpy)(OH2)](SO4); ammonium formate;
In
water;
at 80 ℃;
for 24h;
pH=5.0;
|
94%
6% |
|
With
water; ammonium formate;
[Rh(pentamethylcyclopentadiene)(2,2'-bipyridine)H2O]SO4;
at 80 ℃;
for 1h;
pH=4.5;
Product distribution / selectivity;
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44%
|
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2922-41-0
(p-aminophenyl)alanine
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6482-98-0,23508-35-2,89919-57-3,306-23-0
2-hydroxy-3-(4-hydroxyphenyl)propanoic acid
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-
556-02-5,556-03-6,34537-57-0,55520-40-6,96946-98-4,60-18-4,18875-48-4,25619-78-7,30704-25-7
?Tyr
| Conditions | Yield |
|---|---|
|
With
cis-nitrous acid;
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23508-35-2 Upstream products
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156-39-8
4-hydroxyphenylpiruvic acid
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2922-41-0
(p-aminophenyl)alanine
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52178-61-7
2-hydroxy-3-(4-hydroxyphenyl)acrylic acid
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51095-47-7
methyl 3-(4-hydroxyphenyl)-2-hydroxypropionate
23508-35-2 Downstream products
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15220-05-0
(+/-)-2-hydroxy-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid
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35772-94-2
(+/-)-2-hydroxy-3-(4-hydroxy-3,5-dinitro-phenyl)-propionic acid
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99358-35-7
2-hydroxy-3-(4-hydroxy-3-nitro-phenyl)-propionic acid
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51095-47-7
methyl 3-(4-hydroxyphenyl)-2-hydroxypropionate