Home >Pharmaceutical > (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile
![(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile](/upload/2026/10/9de4595564d347d1982420336655a68f_9723820.png)
- Chemical Name: (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile
- CAS No.: 488787-59-3
Quality products?make an important contribution to long-term revenue and profitability. Reputable supplier selling (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile 488787-59-3 with stock
1.What is the (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile ?
Used in Cardiovascular Medicine:
(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile is used as a beta blocker for the treatment of high blood pressure, angina pectoris, and certain types of irregular heart rhythms. It functions by inhibiting the effects of adrenaline on the heart and blood vessels, leading to a decrease in heart rate and blood pressure, which is beneficial for patients with these conditions.
Used in Post-Heart Attack Care:
(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile is also used as a preventive measure to reduce the risk of recurrent heart attacks. It has been shown to improve survival rates in patients with heart failure, making it an essential component in the post-heart attack care regimen.
Used in Pharmaceutical Formulations:
(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile is typically administered orally in the form of tablets or capsules, making it a convenient and accessible treatment option for patients requiring beta blocker therapy.
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![(1S)-4-[4-(dimethylamino)-1-(4'-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile hemi-(+)-di-(p-toluoyl) tartaric acid salt](/upload/2026/10/e5a8c2dce7a04383803577dcf18ed46b_44f519ee-2f7a-422c-9fd7-cf6a1d08206a.png)
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128173-53-5,912452-31-4
(1S)-4-[4-(dimethylamino)-1-(4'-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile hemi-(+)-di-(p-toluoyl) tartaric acid salt
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![(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile](/upload/2026/10/26bcb36f9f824cddbf30c63e4367afe5_48fa509a-e63b-4538-8385-e7f633a1cf64.png)
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488787-59-3,219861-18-4,481047-48-7
(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
diethyl ether; water;
at 25 ℃;
for 0.5h;
|
100%
|
|
With
sodium hydroxide;
In
diethyl ether; water;
at 25 ℃;
for 0.5h;
|
100%
|
|
With
sodium hydroxide;
In
water; toluene;
at 25 ℃;
for 0.5h;
Solvent;
|
100%
|
|
With
sodium hydroxide;
In
water; toluene;
at 25 ℃;
for 0.5h;
|
100%
|
-
-
C17 H26 N2 O2 Si
-
-
352-13-6
4-flourophenylmagnesium bromide
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488787-59-3,219861-18-4,481047-48-7
(S)-(-)-4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile
| Conditions | Yield |
|---|---|
|
4-flourophenylmagnesium bromide;
With
C45H55FeNP2; copper dichloride;
In
toluene;
at 60 ℃;
for 1h;
Inert atmosphere;
Large scale;
C17H26N2O2Si;
In
toluene;
at 60 ℃;
for 12h;
Reagent/catalyst;
Temperature;
Solvent;
Inert atmosphere;
Large scale;
|
96.4%
|
2.What is the CAS number for (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile ?
The CAS number of (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile is 488787-59-3.
More information of (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile 488787-59-3 are:
|
CAS?Number |
488787-59-3 |
|
Density |
1.22 g/cm3 |
|
Boiling Point |
537.2 °C at 760 mmHg |
|
Flash Point |
278.7 °C |
|
HS CODE |
2926909090 |
|
PSA |
67.49000 |
|
LogP |
2.76738 |
|
Pka |
12.97±0.29(Predicted) |
3.What are another words for (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile ?
Synonyms?for?(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile 488787-59-3:(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile;(S)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxy-1-butyl]-3-(hydroxymethyl)benzonitrile;(S)-Citadiol;
4.What is the molecular formula of (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile?
The chemical formula of ?(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile is?C20H23FN2O2 which containing 20 Carbon atoms,23 Hydrogen atoms,1 Fluorine atoms,2 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile?is 342.413.
5.What is (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile (488787-59-3) used for?
(-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile is a chemical compound that belongs to the class of beta-adrenergic blocking agents, commonly referred to as beta blockers. It is characterized by its ability to block the action of adrenaline on the heart and blood vessels, which results in a reduction of heart rate and lowering of blood pressure. (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile is a crucial medication in the management of various cardiovascular conditions.
Relevant articles related to (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile:
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Article |
Source |
|
PRODUCTION METHOD OF (1S)-4-[4-(DIMETHYLAMINO)-1-(4'-FLUOROPHENYL)-1-HYDROXYBUTYL]-3-(HYDROXYMETHYL)-BENZONITRILE HEMI(+)-DI-(p-TOLUOYL) TARTRATE, AND PRODUCTION METHOD OF (1S)-1-[3-(DIMETHYLAMINO)PROPYL]-1-(4-FLUOROPHENYL)-1,3-DIHYDROISOBENZOFURAN-5-CARBONITRILE AND SALT THEREOF USING THE TARTRATE |
- Paragraph 0020; 0050, (2018/05/03) |
|
PROCESS FOR PRODUCING (1S)-4-[4-(DIMETHYLAMINO)-1-(4'-FLUOROPHENYL)-1-HYDROXYBUTYL]-3-(HYDROXYMETHYL)-BENZONITRILE HEMI(+)-DI-(p-TOLUOYL) TARTARIC ACID SALT, AND PROCESS FOR PRODUCING (1S)-1-[3-(DIMETHYLAMINO)PROPYL]-1-(4-FLUOROPHENYL)-1,3-DIHYDRO-ISOBENZOFURAN-5-CARBO-NITRILE AND SALT THEREOF USING SAID TARTARIC ACID SALT |
- Paragraph 0061, (2018/07/28) |
6.Buy (-)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile with the best price .
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