Home >Pharmaceutical > 4-Bromocinnamic acid
- Chemical Name: 4-Bromocinnamic acid
- CAS No.: 1200-07-3
Quality Manufacturer Supply High Purity 99% 4-Bromocinnamic acid 1200-07-3 with Reasonable Price
- Molecular Formula: C9H7BrO2
- Molecular Weight: 227.057
- Appearance/Colour: colorless or white crystalline solid
- Vapor Pressure: 2.43E-05mmHg at 25°C
- Melting Point: 260-265 °C
- Boiling Point: 344.9 °C at 760 mmHg
- PKA: 4.35±0.10(Predicted)
- Flash Point: 162.4 °C
- PSA： 37.30000
- Density: 1.607 g/cm3
- LogP: 2.54690
4-Bromocinnamic acid(Cas 1200-07-3) Usage
InChI:InChI=1/C9H7BrO2/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6H,(H,11,12)/p-1/b6-3+
1200-07-3 Relevant articles
Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport
Terai, Takuya,Kohno, Moe,Boncompain, Gaelle,Sugiyama, Shigeru,Saito, Nae,Fujikake, Ryo,Ueno, Tasuku,Komatsu, Toru,Hanaoka, Kenjiro,Okabe, Takayoshi,Urano, Yasuteru,Perez, Franck,Nagano, Tetsuo
, p. 10464 - 10467 (2015)
Artificial ligands of streptavidin (ALiS...
Phenanthroline functionalized polyacrylonitrile fiber with Pd(0) nanoparticles as a highly active catalyst for the Heck reaction
Xiao, Jian,Zhang, Haonan,Ejike, Anyaegbu Chima,Wang, Lu,Tao, Minli,Zhang, Wenqin
, (2021)
A series of polyacrylonitrile fibers (PA...
Design, synthesis and neuroprotective activities of novel cinnamide derivatives containing benzylpiperazine moiety
Zhong, Yan,Li, Xiaofeng,Zhang, Aixia,Xu, Yi,Li, Ping,Wu, Bin
, p. 1366 - 1373 (2018)
A new series of cinnamide derivatives 6a...
Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery
Devine, William,Woodring, Jennifer L.,Swaminathan, Uma,Amata, Emanuele,Patel, Gautam,Erath, Jessey,Roncal, Norma E.,Lee, Patricia J.,Leed, Susan E.,Rodriguez, Ana,Mensa-Wilmot, Kojo,Sciotti, Richard J.,Pollastri, Michael P.
, p. 5522 - 5537 (2015)
Tropical protozoal infections are a sign...
A Simple and straightforward synthesis of cinnamic acids and ylidene malononitriles via knoevenagel condensation employing dabco as catalyst
Nagalakshmi,Diwakar,Govindh,Gopal Reddy,Venu,Bhargavi,Prasanna Devi,Murthy,Siddaiah
, p. 1561 - 1564 (2017)
An efficient method for the synthesis of...
Synthesis, photophysics, and electroluminescence of conjugated poly(p-phenylenevinylene) derivatives with 1,3,4-oxadiazoles in the backbone
Mikroyannidis, John A.,Spiliopoulos, Ioakim K.,Kasimis, Theodoros S.,Kulkarni, Abhishek P.,Jenekhe, Samson A.
, p. 9295 - 9302 (2003)
Starting from 4-bromobenzaldehyde or 1,4...
Diphenylamino-substituted tristyryl: Vs. triphenyl isocyanurates: Improved conjugation has minimal impact on two-photon absorption
Triadon, Amédée,Ngo Ndimba, Alphonsine,Richy, Nicolas,Amar, Anissa,Boucekkine, Abdou,Roisnel, Thierry,Cifuentes, Marie P.,Humphrey, Mark G.,Blanchard-Desce, Mireille,Mongin, Olivier,Paul, Frédéric
, p. 11289 - 11293 (2018)
This contribution reports the synthesis ...
Crystallization-Based Synthetic Route to Antimalarial Agent BRD5018: Diazocene Ring Formation via a Staudinger-aza-Wittig Reaction on an Azetidine-Ribose Template
Balla, Venkata Sasidhar,Bathula, Srikanth,Fang, Francis G.,Girish, Dixit,Gotoda, Masaharu,Gusovsky, Fabian,Kalla, Vijay,Khile, Anil Shahaji,Melillo, Bruno,Mitasev, Branko,Rayaprolu, Pavan Kumar,Schreiber, Stuart L.,Sugandham, Srinivasa Rao,Talabhakthula, Ravi Kumar,Terli, Chiranjeevi,Vaddi, Anand,Vikram, Venugopalarao,Yang, Jiong
, (2021/10/01)
The development of an entirely crystalli...
Iron-catalyzed domino decarboxylation-oxidation of α,β-unsaturated carboxylic acids enabled aldehyde C-H methylation
Gong, Pei-Xue,Xu, Fangning,Cheng, Lu,Gong, Xu,Zhang, Jie,Gu, Wei-Jin,Han, Wei
supporting information, p. 5905 - 5908 (2021/06/18)
A practical and general iron-catalyzed d...
Amino Group Functionalized Hf-Based Metal-Organic Framework for Knoevenagel-Doebner Condensation
Das, Aniruddha,Anbu, Nagaraj,Gogoi, Chiranjib,Dhakshinamoorthy, Amarajothi,Biswas, Shyam
, p. 3396 - 3403 (2021/08/20)
A Hf(IV) metal-organic framework (MOF) w...
Enantioselective Rauhut–Currier Reaction with β-Substituted Acrylamides Catalyzed by N-Heterocyclic Carbenes
Pitchumani, Venkatachalam,Breugst, Martin,Lupton, David W.
supporting information, p. 9413 - 9418 (2021/12/09)
β-Substituted acrylamides have low elect...
1200-07-3 Process route
-
-
112595-55-8
(2RS,3SR)-2,3-dibromo-3-(4-bromophenyl)propanoic acid
-
-
7732-18-5
water
-
-
1200-07-3,5676-63-1,17916-60-8
trans-4-bromocinnamic acid
-
-
778641-02-4
1-bromo-4-(2-bromovinyl)benzene
-
-
1122-91-4
4-bromo-benzaldehyde
| Conditions | Yield |
|---|---|
|
|
-
-
141-82-2
malonic acid
-
-
1122-91-4
4-bromo-benzaldehyde
-
-
1200-07-3,5676-63-1,17916-60-8
trans-4-bromocinnamic acid
| Conditions | Yield |
|---|---|
|
With
piperidine; pyridine;
at 90 ℃;
for 1h;
|
98%
|
|
With
piperazine;
for 0.0666667h;
microwave irradiation;
|
95%
|
|
With
1,8-diazabicyclo[5.4.0]undec-7-ene; 3-amino propanoic acid;
In
ethanol;
at 20 ℃;
stereoselective reaction;
|
95%
|
|
With
piperidine;
at 85 ℃;
for 6h;
Ionic liquid;
|
93%
|
|
With
piperidine; pyridine;
at 100 - 105 ℃;
for 2h;
Large scale;
|
93.7%
|
|
With
piperidine; pyridine;
for 6h;
Heating;
|
90%
|
|
With
piperidine; pyridine;
Reflux;
|
90%
|
|
With
piperidine; pyridine;
at 110 ℃;
|
89%
|
|
malonic acid; 4-bromo-benzaldehyde;
With
piperidine; pyridine;
Reflux;
With
hydrogenchloride;
In
water;
optical yield given as %de;
Cooling with ice;
|
88%
|
|
With
pyridine;
Heating;
|
85%
|
|
With
piperidine; pyridine;
for 0.333333h;
Microwave irradiation;
|
84%
|
|
With
piperidine; pyridine;
for 1h;
Reflux;
|
83%
|
|
With
piperidine; pyridine;
for 12h;
Inert atmosphere;
Reflux;
|
82%
|
|
With
piperidine; pyridine;
for 20h;
Heating;
|
63%
|
|
With
piperidine; pyridine;
at 95 ℃;
|
50%
|
|
With
ammonia;
Erhitzen des nach dem Eindampfen verbliebenen Rueckstands;
|
|
|
With
piperidine; pyridine;
|
|
|
malonic acid; 4-bromo-benzaldehyde;
With
piperidine; pyridine;
With
hydrogenchloride;
Heating;
|
|
|
With
piperidine;
In
pyridine;
|
|
|
With
piperidine;
In
pyridine;
at 80 - 90 ℃;
for 24h;
|
|
|
With
piperidine; pyridine;
at 80 - 90 ℃;
for 24h;
|
|
|
With
piperidine; pyridine;
at 80 ℃;
for 24h;
|
|
|
malonic acid; 4-bromo-benzaldehyde;
With
piperidine; pyridine;
at 80 - 115 ℃;
With
hydrogenchloride;
In
water;
at 20 ℃;
|
|
|
With
piperidine; pyridine;
for 1h;
Reflux;
|
|
|
With
piperidine; pyridine;
at 85 ℃;
for 24h;
|
|
|
With
piperidine; pyridine;
at 85 ℃;
for 24h;
|
|
|
With
piperidine; pyridine;
at 115 ℃;
Reflux;
|
|
|
With
piperidine; pyridine;
for 8h;
Reflux;
|
|
|
With
piperidine;
In
dimethyl sulfoxide;
at 100 ℃;
for 12h;
Schlenk technique;
|
|
|
With
pyridine;
for 12h;
Reflux;
|
|
|
With
piperidine;
In
pyridine;
at 85 ℃;
for 6h;
|
|
|
With
piperidine;
In
dimethyl sulfoxide;
at 60 ℃;
for 0.333333h;
diastereoselective reaction;
Microwave irradiation;
Sealed tube;
|
|
|
With
pyridine;
In
N,N-dimethyl-formamide;
at 90 ℃;
for 5h;
|
|
|
With
piperidine; pyridine;
for 2h;
Reflux;
|
|
|
With
piperidine;
for 0.00416667h;
Microwave irradiation;
|
|
|
With
piperidine; pyridine;
at 70 - 80 ℃;
|
|
|
With
pyridine;
In
N,N-dimethyl-formamide;
at 150 ℃;
|
|
|
With
piperidine; pyridine;
for 12h;
Reflux;
Inert atmosphere;
|
|
|
With
[Hf6O4(OH)4(2,2’-diamino-[1,1’-biphenyl]-4,4’-dicarboxylic acid)6]*10H2O*5DMF;
In
N,N-dimethyl-formamide; toluene;
at 80 ℃;
for 24h;
Schlenk technique;
|
|
|
With
piperidine; pyridine;
at 90 ℃;
for 16h;
|
1200-07-3 Upstream products
-
2393-18-2
p-aminocinnamic acid
-
108-24-7
acetic anhydride
-
1122-91-4
4-bromo-benzaldehyde
-
141-82-2
malonic acid
1200-07-3 Downstream products
-
586-76-5
4-Bromobenzoic acid
-
13565-09-8
4-bromocinnamoyl chloride
-
25574-11-2
3-(4-bromophenyl)propanol
-
66432-12-0
N-[(E)-2-(4-Bromo-phenyl)-vinyl]-formamide